The Ontario Neurotrauma Foundation has identified a need to increase its knowledge, expertise, and capacity in Implementation Science to more effectively support its constituents within their three prioriy areas: treatment of Traumatic Brain Injuries, treatment of Spinal Cord Injuries, and Prevention. Through a partnership with the NIRN, this project seeks to achieve three distinct yet related goals. This first is to develop ONF's internal implementation capacity and retool the current infrastructure to support an aligned implementation science informed approach. The second goal is to build the implementation capacity of six rehabiliation centers (Calgary, Edmonton, London, Montreal, Toronto, and Quebec) across three provincies (Alberta, Ontario, and Quebec) by targeting three domains of secondary complications for individuals with spinal cord injuries. These domains include the treatment and prevention of pressure ulcers, managing pain, and bladder control. This effort will help build a national implementation-informed approach for selecting evidence-based practices and ensuring the implementation fluency of key stakeholders. A SCI Knowledge Mobilization Network has been created to serve as the infrastructure to support the work across three provinces in this initial pilot with intentions of a systematic stragey for including the other provinces and territories. The final goal of this project is to prepare the original sites to serve as Centers of Excellent to engage in scaling up within their province and to scale across the continuum of care–acute care, rehabilitation, and the community.