Existing guidelines and strategies for the prevention or reduction of obesity were developed from an evidence base of research that typically excluded participation by people with disabilities. There is a critical need to promote more inclusive community-based obesity prevention programs that represent the needs of youth and young adults with disabilities from diverse race/ethnic backgrounds. This project is using a systematic approach to develop, identify, and adapt strategies and practices supporting participation of youth/young adults with disabilities in community-based obesity-prevention programs. It is also studying the prevalence, risk factors, and health consequences of obesity/overweight in adolescents and young adults with disabilities from culturally diverse backgrounds and developing an infrastructure for translating obesity research into practice and policy for youth and young adults with physical and cognitive disabilities. The project is funded by the U.S. Department of Education, National Institute on Disability and Rehabilitation Research (NIDRR) as a Disability and Rehabilitation Research Project (DRRP).