The Nuanced Negative: Meanings of a Negative Diagnostic Result in Clinical Exome Sequencing

Skinner, D., Raspberry, K. A., & King, M.

From the abstract: "In this paper we examine the uncertainties and nuances of the negative result from genome sequencing and how both clinicians and patients make meaning of it as revealed in ethnographic observations of the clinic session where results are returned, and in interviews with patients. We find that clinicians and patients construct the meaning of a negative result in ways that are uncertain, contingent, and multivalent; but invested with optimism, promise, and potentiality."

Citation: Skinner, D., Raspberry, K. A., & King, M. (2016). The nuanced negative: Meanings of a negative diagnostic result in clinical exome sequencing. Sociology of Health & Illness, 38, 1303-1317.
DOI: 10.1111/1467-9566.12460